Searchable abstracts of presentations at key conferences in endocrinology

ea0011p280 | Diabetes, metabolism and cardiovascular | ECE2006

Regulation of brain-derived resistin and FIAF in a novel hypothalamic neuronal cell line

Brown RE , Imran A , Belsham DD , Ur E , Wilkinson M

Adipokines such as resistin and FIAF (fasting-induced adipose factor) are predominantly, but not exclusively, expressed in adipose tissue and may modulate insulin sensitivity and lipid metabolism. We reported that resistin and fiaf mRNA, and resistin protein, are detectable in the mouse hypothalamus and pituitary gland (see eg. Wiesner et al. 2004). We are investigating the regulation of these genes in a novel hypothalamic neuronal cell line (n-1; Belsham ...